4-PHENYL-INDOLE DERIVATIVES AND RELATED USES

The present disclosure relates to compounds of Formula (I):and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for modulating PD-1 activity, PD-L1 activity, and/or the PD-1...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	THAVORNSIN, Nopparat, DEESIRI, Sirikan, CHAROENPAKDEE, Chayan, PISITKUN, Trairak, AMPAWA, Supanan, RATTANANGKOOL, Eakkaphon, SRISA, Jakkrit, CHAIYAKUNVAT, Pongkorn, DUNKOKSUNG, Wilasinee, BURANAPRADITKUN, Supranee, VILAIVAN, Tirayut, HIRANKARN, Nattiya, UDOMNILOBOL, Udomsak, NALINRATANA, Nonthaneth, PRUEKSARITANONT, Thomayant, RUENGSATRA, Tanachote, SOPONPONG, Jakapun, SONGTHAMMANUPHAP, Songkiat
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present disclosure relates to compounds of Formula (I):and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for modulating PD-1 activity, PD-L1 activity, and/or the PD-1/PD-L1 interaction and may be used in the treatment of disorders in which PD-1 activity, PD-L1 activity, and/or PD-1/PD-L1 interaction is implicated, such as cancer.