EFFECTOR PROTEINS AND METHODS OF USE

The present disclosure provides compositions of effector proteins. The compositions may comprise engineered guide nucleic acids. Also disclosed are the methods and systems for detecting and modifying target nucleic acids using the same. The compositions may provide nucleic acid modification and/or d...

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Bibliographische Detailangaben
Hauptverfasser: Mckay, Bridget Ann Paine, Rauch, Benjamin Julius, BROUGHTON, James Paul, Verosloff, Matthew, Chen, Janice Sha, Wright, William Douglass, Ching, Jesus, Kreindler, Lior, Fasching, Clare Louise, Harrington, Lucas Benjamin, Paez-Espino, David
Format: Patent
Sprache:eng
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Zusammenfassung:The present disclosure provides compositions of effector proteins. The compositions may comprise engineered guide nucleic acids. Also disclosed are the methods and systems for detecting and modifying target nucleic acids using the same. The compositions may provide nucleic acid modification and/or detection at relatively high temperatures.