LENALIDOMIDE PROCESS

The present invention provides to an improved process for the preparation of new and high purity crystalline Form SRA of 3-(4-amino-1-oxoisoindolin-2-yl) piperidine-2, 6-dione of formula (I)The pure crystalline Form SRA of compound of formula (I) obtained by the process of present invention is havin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Tripathi, Yogesh, Panda, Bijan Kumar, Chaturvedi, Akshay Kant, Satyaveer, Chaturvedi, Deepali, Bala, Saroj, Baqer, Mohammad
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention provides to an improved process for the preparation of new and high purity crystalline Form SRA of 3-(4-amino-1-oxoisoindolin-2-yl) piperidine-2, 6-dione of formula (I)The pure crystalline Form SRA of compound of formula (I) obtained by the process of present invention is having purity of greater than 99.9% (area % by HPLC).Lenalidomide (I) pure crystalline Form SRA is useful in the treatment of cancer, inflammatory diseases, autoimmune diseases and Multiple myeloma.