ACAT1 INHIBITOR AND METHOD OF USE IN THE TREATMENT OF DISEASE

ACAT1 INHIBITOR AND METHOD OF USE IN THE TREATMENT OF DISEASE

A high potency, brain-permeable compound that inhibits Acyl-CoA:Cholesterol Acyltransferase 1 (ACAT1) activity is provided as are pharmaceutical compositions and methods for treating a disease, disorder, or condition mediated by ACAT1.

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Bibliographische Detailangaben
Hauptverfasser: CHANG, Ta Yuan, CHANG, Catherine C.Y, DE LA TORRE, Adrianna
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:A high potency, brain-permeable compound that inhibits Acyl-CoA:Cholesterol Acyltransferase 1 (ACAT1) activity is provided as are pharmaceutical compositions and methods for treating a disease, disorder, or condition mediated by ACAT1.