KETOROLAC LIQUID COMPOSITION, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

A ketorolac liquid composition, a preparation method therefor, and an application thereof are provided. The ketorolac liquid composition contains ketorolac tromethamine, a stabilizer, a buffer, an osmotic pressure regulator, and a pH regulator. The ketorolac liquid composition does not contain ethan...

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Bibliographische Detailangaben
Hauptverfasser: FU, Jun, YING, Shuhuan, LIU, Shuang, CHEN, Zhixiang, GUO, Zhen, CHEN, Bangyin, WANG, Tingting
Format: Patent
Sprache:eng
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Zusammenfassung:A ketorolac liquid composition, a preparation method therefor, and an application thereof are provided. The ketorolac liquid composition contains ketorolac tromethamine, a stabilizer, a buffer, an osmotic pressure regulator, and a pH regulator. The ketorolac liquid composition does not contain ethanol. The concentration of ketorolac tromethamine is 0.15 mmol/L-160.00 mmol/L, and the concentration refers to a ratio of a molar amount of the ketorolac tromethamine to a volume of the ketorolac liquid composition. The ketorolac liquid composition does not contain an organic solvent, has stable physical and chemical properties, and has less in-vivo irritation.