NOVEL PLK1 PROTEIN DEGRADATION-INDUCING COMPOUND

The present invention relates to a PLK1 protein degradation inducing compound, a preparation method thereof, and a use thereof. Compounds of the present invention target PLK1 and BRD4 to degrade PLK1, and decompose BRD4 to a suitable level within the scope of causing no side effects, and thus can be...

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Bibliographische Detailangaben
Hauptverfasser:	Min, Im Suk, Kim, Seong Hoon, Ryu, Hye Guk, Kang, Keum Young
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to a PLK1 protein degradation inducing compound, a preparation method thereof, and a use thereof. Compounds of the present invention target PLK1 and BRD4 to degrade PLK1, and decompose BRD4 to a suitable level within the scope of causing no side effects, and thus can be very advantageously used for prevention or treatment of cancer or neural disease.