METHODS AND KITS FOR ENRICHING FOR POLYNUCLEOTIDES

Growing demand in RNA-targeted therapies and promise of miRNA-based drugs creates a need for tools that can accurately identify and quantify miRNA:target interactions at scale. Chimeric miRNA:mRNA reads provide a direct read out of miRNA targets by capturing interaction of miRNA and targeted transcr...

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Bibliographische Detailangaben
Hauptverfasser:	Shishkin, Alexander A, Shen, Kylie An-yi, Manakou, Siarhei
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Growing demand in RNA-targeted therapies and promise of miRNA-based drugs creates a need for tools that can accurately identify and quantify miRNA:target interactions at scale. Chimeric miRNA:mRNA reads provide a direct read out of miRNA targets by capturing interaction of miRNA and targeted transcripts. In aspects described herein are methods for enriching microRNA (miRNA) targeted RNA molecules. In yet further aspects described herein are methods for enriching chimeric microRNA (miRNA)-targeted RNA molecules.