RPE CELL POPULATIONS AND METHODS OF GENERATING SAME

A population of human polygonal RPE cells is disclosed. At least 95% of the cells thereof co-express premelanosome protein (PMEL17) and cellular retinaldehyde binding protein (CRALBP), wherein the trans-epithelial electrical resistance of the cells is greater than 100 ohms. Methods of generating sam...

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Bibliographische Detailangaben
Hauptverfasser: Wiser, Ofer, Rosenberg Belmaker, Lior Ann, Bohana-Kashtan, Osnat
Format: Patent
Sprache:eng
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Zusammenfassung:A population of human polygonal RPE cells is disclosed. At least 95% of the cells thereof co-express premelanosome protein (PMEL17) and cellular retinaldehyde binding protein (CRALBP), wherein the trans-epithelial electrical resistance of the cells is greater than 100 ohms. Methods of generating same are also disclosed.