METHOD AND SYSTEM FOR CALIBRATION OF BRAIN HEMODYNAMICS

In order to enable more accurate calibration of brain, there is provided a system for creating a hemodynamic brain atlas for calibration of brain hemodynamics. The system comprises a non-invasive transcranial neurostimulation device, a non-invasive neuromonitoring device, and a computing device. The...

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Hauptverfasser: Westerink, Joanne Henriëtte Desirée Monique, Huijbers, Willem, Leufkens, Timmy Robertus Maria, van Dooren, Marieke, Lamerichs, Rudolf Mathias Johannes Nicolaas, Denissen, Adrianus Johannes Maria, Van Ee, Raymond, Matters, Marco
Format: Patent
Sprache:eng
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Zusammenfassung:In order to enable more accurate calibration of brain, there is provided a system for creating a hemodynamic brain atlas for calibration of brain hemodynamics. The system comprises a non-invasive transcranial neurostimulation device, a non-invasive neuromonitoring device, and a computing device. The non-invasive transcranial neurostimulation device is configured to induce neuronal activity to evoke a hemodynamic response in a target region of interest (ROI) of a brain of a human subject. The non-invasive neuromonitoring device is configured to monitor the evoked hemodynamic response in the target ROI. The computing device configured to determine a set of parameters representing a hemodynamic response function, HRF, of the evoked hemodynamic response in the target ROI, and to associate the set of parameters of the HRF with the target ROI to form the hemodynamic brain atlas.