GASTRO-RESISTANT HIGH-STRENGTH FORMULATION CONTAINING POSACONAZOLE

The present invention relates to a gastro-resistant high-strength unit dosage form comprising a solid solution prepared by hot-melt extrusion, whereby the solid solution contains 300 mg posaconazole and an enteric polymer in a specific weight ratio. The unit dosage form may be a capsule or optionall...

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Bibliographische Detailangaben
Hauptverfasser: PRATHAP, Vamshi Ramana, FITZNER, Ansgar, SCHLEHAHN, Hendrik, RALLABANDI, Bala Ramesha Chary, MUPKALKER, Ashwini Kumar, VELCHURI, Srikanth, KALAMATA, Venkatasimhadri Naidu, MADALLAPALLI, Kiran Kumar
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a gastro-resistant high-strength unit dosage form comprising a solid solution prepared by hot-melt extrusion, whereby the solid solution contains 300 mg posaconazole and an enteric polymer in a specific weight ratio. The unit dosage form may be a capsule or optionally film-coated tablet.