AN IMPROVED PROCESS FOR THE PREPARATION OF (4R)-1-[(2R,4R,5R)-3,3-DIFLUORO-4-HYDROXY-5-(HYDROXYMETHYL) OXOLAN-2-YL]-4-HYDROXY-1,3-DIAZINAN-2ONE AND ITS INTERMEDIATE COMPOUNDS

AN IMPROVED PROCESS FOR THE PREPARATION OF (4R)-1-[(2R,4R,5R)-3,3-DIFLUORO-4-HYDROXY-5-(HYDROXYMETHYL) OXOLAN-2-YL]-4-HYDROXY-1,3-DIAZINAN-2ONE AND ITS INTERMEDIATE COMPOUNDS

The present invention relates to an improved process for the preparation of (4R)-1-[(2R, 4R, 5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl) oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one compound of formula-1 and its intermediate compounds. [Formula should be inserted here]. The present invention also rela...

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Bibliographische Detailangaben
Hauptverfasser: GADE, Srinivas Reddy, GOPULARAM, Shiva Shankar Goud, CHALLA, Suresh, SRINIVASAN, Thirumalai Rajan, SAJJA, Eswaraiah
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Zusammenfassung:The present invention relates to an improved process for the preparation of (4R)-1-[(2R, 4R, 5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl) oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one compound of formula-1 and its intermediate compounds. [Formula should be inserted here]. The present invention also relates to the process for the purification of (4R)-1-[(2R, 4R, 5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl) oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one compound of formula-1 to get pure compound of formula-1.