DETERMINATION OF A SUBJECT SPECIFIC HEMODYNAMIC RESPONSE FUNCTION

Disclosed herein is a medical system (100, 300) where execution of machine executable instructions (120) causes a computational system (104) to: receive (200) a time series of a R2-star map (122) for a brain volume (500); receive (202) a stimulus signal (124) descriptive of an occurrence of a sensor...

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Bibliographische Detailangaben
Hauptverfasser:	Westerink, Joanne Henriëtte Desirée Monique, Leufkens, Timmy Robertus Maria, Lamerichs, Rudolf Mathias Johannes Nicolaas
Format:	Patent
Sprache:	eng
Schlagworte:	DIAGNOSIS HUMAN NECESSITIES HYGIENE IDENTIFICATION MEASURING MEASURING ELECTRIC VARIABLES MEASURING MAGNETIC VARIABLES MEDICAL OR VETERINARY SCIENCE PHYSICS SURGERY TESTING
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Beschreibung
Zusammenfassung:	Disclosed herein is a medical system (100, 300) where execution of machine executable instructions (120) causes a computational system (104) to: receive (200) a time series of a R2-star map (122) for a brain volume (500); receive (202) a stimulus signal (124) descriptive of an occurrence of a sensory stimulus; receive (204) a selection of one or more seed voxels (126) identified in the time series of the R2-star map; calculate (206) a denoised time series of the R2-star map (128); calculate (208) a correlation map (130) between the seed voxels and the denoised time series of the R2-star map; determine (210) an activated region (132) of the brain volume using voxels identified in the correlation map; provide (212) a hemodynamic response (134) function for each voxel and each occurrence of the sensory stimulus; and provide (214) a subject specific hemodynamic response function (136) by averaging the hemodynamic response functions.