COMPOUNDS FOR FGFRS INHIBITORS

A compound having the following structure of Formula (I):or a stereoisomer, salt, or tautomer thereof, wherein R1, R2, R5, A, B, X, and Y are as defined herein. Pharmaceutical composition comprising the compounds, and their use in methods of treating diseases are also described.

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Bibliographische Detailangaben
Hauptverfasser:	Robinson, John E, Smith, Aaron Christopher, Fulton, Jennifer, Fischer, John P, Salituro, Leah J, Scaggs, Toya D, Vine, Logan E, Mejia, Macedonio J, Rodriguez, Martha E, Newhouse, Bradley J, Bettendorf, Tanna, Chicarelli, Mark Joseph, Chatterjee, Payal, Dahlke, Joshua, Rieger, Robert A, Jalluri, Ravi Kumar, Fell, Jay Bradford, Malinky, Cori A
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	A compound having the following structure of Formula (I):or a stereoisomer, salt, or tautomer thereof, wherein R1, R2, R5, A, B, X, and Y are as defined herein. Pharmaceutical composition comprising the compounds, and their use in methods of treating diseases are also described.