EXTRACELLULAR VESICLE-ENRICHED SECRETOME COMPOSITION DERIVED FROM INDUCED PLURIPOTENT STEM CELL DERIVED-MICROGLIA AND METHODS OF USE THEREOF

The present disclosure provides extracellular vesicle-enriched compositions derived from iPSC-derived microglia. Further provided herein are methods for using the extracellular vesicle-enriched compositions from iPSC-derived microglia in screening assays to discover properties, including therapeutic...

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Bibliographische Detailangaben
Hauptverfasser:	NELSON, Dana, SMITH, Steve, LIVINGSTON, Megan K, HARMS, Lisa, HAMRICK, Michele, TOMOTOSHI, Kimihiko, BAKSHY, Kiranmayee, CARLSON, Coby, RENAULT, Nisa, WONG, Jacquelyn
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present disclosure provides extracellular vesicle-enriched compositions derived from iPSC-derived microglia. Further provided herein are methods for using the extracellular vesicle-enriched compositions from iPSC-derived microglia in screening assays to discover properties, including therapeutic properties.