Non-Invasive Assessment Of Glymphatic Flow And Neurodegeneration From A Wearable Device

A computer-implemented method and system includes accessing neurophysiological and neurovascular data recorded during sleep. A function mapping is executed from said neurophysiological and neurovascular data to a target that is one of a glymphatic flow marker, a molecular analysis marker of neurodeg...

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Hauptverfasser: Dagum, Paul, Kaplan, Jonathan I, Weber, Carl J, Giovangrandi, Laurent B, Whipple, Nathan, Kovacs, Gregory T.A, Student, Joerg C
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A computer-implemented method and system includes accessing neurophysiological and neurovascular data recorded during sleep. A function mapping is executed from said neurophysiological and neurovascular data to a target that is one of a glymphatic flow marker, a molecular analysis marker of neurodegeneration, or a neuroimaging marker of neurodegeneration. A target prediction model is output based on the function mapping. The target prediction model can receive new neurophysiological and neurovascular data and output a predicted marker of neurodegeneration.