BIOLOGICALLY CONTAINED BACTERIA AND USES THEREOF

The present disclosure provides biocontainment methods and mechanisms that prevent modified cells from escaping their intended environment(s) while enabling the survival and replication of the modified cells where intended. This is achieved by linking the viability of the modified cells to the prese...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Russ, IV, Zachary Nicholas, DeLoache, William Cain, Popov, Lauren, Whitaker, Weston Robert, Stanley Shepherd, Elizabeth Joy
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present disclosure provides biocontainment methods and mechanisms that prevent modified cells from escaping their intended environment(s) while enabling the survival and replication of the modified cells where intended. This is achieved by linking the viability of the modified cells to the presence of a control molecule that is exogenously supplied to define the location and time in which cells are capable of growing.