MULTI-FUNCTIONAL CONDUCTING POLYMER COATING ON VASCULAR ACCESS DEVICES

MULTI-FUNCTIONAL CONDUCTING POLYMER COATING ON VASCULAR ACCESS DEVICES

Provided are conductive films including a heparin modified polymer. The heparin modified polymer comprises heparin covalently bound to a beta-substituted monomer having a conjugated backbone that is co-polymerized to its non-functionalized pair. The heparin modified polymer on a conductive film can...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
1. Verfasser: Forciniti, Leandro
Format: Patent
Sprache:eng
Schlagworte:
AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
CHEMISTRY
COMPOSITIONS BASED THEREON
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
GENERAL PROCESSES OF COMPOUNDING
HUMAN NECESSITIES
HYGIENE
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
ORGANIC MACROMOLECULAR COMPOUNDS
THEIR PREPARATION OR CHEMICAL WORKING-UP
WORKING-UP
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Provided are conductive films including a heparin modified polymer. The heparin modified polymer comprises heparin covalently bound to a beta-substituted monomer having a conjugated backbone that is co-polymerized to its non-functionalized pair. The heparin modified polymer on a conductive film can be manufactured by co-polymerizing a beta-substituted monomer with a non-functionalized monomer to form a polymer on a conductive film. The polymer is reacted with N,N′-Dicyclohexylcarbodiimide (DCC) and acetic acid to form an anhydride of the polymer on the conductive film. The anhydride is then reacted with heparin to form the heparin modified polymer on the conductive film. Medical devices having a coating comprising the conductive film are also described.