A PROCESS FOR THE PREPARATION OF 2-NITRO-4-(METHYLSULFONYL)BENZOIC ACID

A PROCESS FOR THE PREPARATION OF 2-NITRO-4-(METHYLSULFONYL)BENZOIC ACID

The present disclosure relates to a process for the preparation of 2-nitro-4-methylsulfonyl benzoic acid (NMSBA). The process comprises reacting 1-chloro-2-nitro-4-methyl sulfonyl benzene (chloro NMSB) with a compound of Formula (II) by using a base in a fluid medium at a first predetermined tempera...

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Bibliographische Detailangaben
Hauptverfasser: MATHUR, Suchet Saran, SATHE, Shekhar Vishwanath, PRAJAPATI, Vinodkumar Jethuram, SINGH, Vikram Naresh, MAIRH, Mithilesh Kumar, KSHIRSAGAR, Kedar Parshuram
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present disclosure relates to a process for the preparation of 2-nitro-4-methylsulfonyl benzoic acid (NMSBA). The process comprises reacting 1-chloro-2-nitro-4-methyl sulfonyl benzene (chloro NMSB) with a compound of Formula (II) by using a base in a fluid medium at a first predetermined temperature to obtain a compound of Formula (III). The compound of Formula (III) is reacted with an oxidizing agent optionally in the presence of a catalyst under stirring to obtain a mixture. Air is optionally passed through the mixture. The mixture is heated at a second predetermined temperature for a predetermined time period to obtain a product mixture comprising 2-Nitro-4-(methyl sulfonyl) benzoic acid. The process of the present disclosure is simple, economical and environment-friendly.