METHODS FOR USING A HYPOMETHYLATING AGENT TO TREAT DISEASES AND DISORDERS BASED ON GENE MUTATION PROFILES

Provided herein are methods of using a hypomethylating agent (e.g., 5-azacytidine or decitabine), optionally in combination with one or more additional therapeutic agents or therapies, to treat diseases and disorders including cancers such as but not limited to acute myeloid leukemia (AML), and myel...

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Hauptverfasser:	LA TORRE, Ignazia, SKIKNE, Barry Sim, BEACH, Charles Lee, SEE, Wendy Laurene, UGIDOS GUERRERO, Manuel, RISUEÑO PÉREZ, Alberto, THAKURTA, Anjan Guha, LOPES DE MENEZES, Daniel Elvyn
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided herein are methods of using a hypomethylating agent (e.g., 5-azacytidine or decitabine), optionally in combination with one or more additional therapeutic agents or therapies, to treat diseases and disorders including cancers such as but not limited to acute myeloid leukemia (AML), and myelodysplastic syndromes (MDS), based on gene mutation profiles of the diseases and disorders.