METHOD FOR PRODUCING PYRROLIDINE COMPOUND

METHOD FOR PRODUCING PYRROLIDINE COMPOUND

The present invention provides a method suitable for industrial production of a compound of formula (V): (V) comprising a step of subjecting a compound (IV) to an asymmetric reductive amination reaction in the presence of a metal complex comprising a chiral ligand and subjecting this product to puri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ABE, Takashi, ODA, Tsuneo, YAMASHITA, Hironori, YABE, Osamu, YAMADA, Masatoshi, HIRANO, Sayuri, KAJITA, Yuichi
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention provides a method suitable for industrial production of a compound of formula (V): (V) comprising a step of subjecting a compound (IV) to an asymmetric reductive amination reaction in the presence of a metal complex comprising a chiral ligand and subjecting this product to purification using salt formation with N-(4-methylbenzene-1-sulfonyl)-L-phenylalanine.