NON-VIRAL DNA VECTORS EXPRESSING THERAPEUTIC ANTIBODIES AND USES THEREOF

The application describes methods and compositions comprising ceDNA vectors useful for the expression of antibodies and antigen-binding fragments thereof in a cell, tissue or subject, and methods of treatment and/or prevention of various diseases, disorders and cancers.

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Bibliographische Detailangaben
Hauptverfasser: Gagne, Raphael, Samayoa, Phillip, Jindal, Siddharth, Kerr, Douglas Anthony, Silver, Nathaniel
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The application describes methods and compositions comprising ceDNA vectors useful for the expression of antibodies and antigen-binding fragments thereof in a cell, tissue or subject, and methods of treatment and/or prevention of various diseases, disorders and cancers.