METHOD FOR PREPARING CO-PROCESSED EXCIPIENT GRANULES

METHOD FOR PREPARING CO-PROCESSED EXCIPIENT GRANULES

The invention relates to a method for preparing co-processed excipient granules using a co-rotating twin-screw extruder, wherein at least one binder and at least one superdisintegrant are granulated together, and wherein the binder and the superdisintegrant are introduced into the extruder in differ...

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Hauptverfasser: JASPERS, Maarten, HEBBINK, Gerrit Albert, VAN HAANDEL, Mara Maria Wilhelmina, VAN LAARHOVEN, Bas, KULKARNI, Sri Sharath
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator JASPERS, Maarten
HEBBINK, Gerrit Albert
VAN HAANDEL, Mara Maria Wilhelmina
VAN LAARHOVEN, Bas
KULKARNI, Sri Sharath
description The invention relates to a method for preparing co-processed excipient granules using a co-rotating twin-screw extruder, wherein at least one binder and at least one superdisintegrant are granulated together, and wherein the binder and the superdisintegrant are introduced into the extruder in different points. The invention also relates to co-processed excipient granules obtained or obtainable by the method. The invention further relates to the use of the co-processed excipient granules in a tableting process.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title METHOD FOR PREPARING CO-PROCESSED EXCIPIENT GRANULES
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