METHOD FOR PREPARING CO-PROCESSED EXCIPIENT GRANULES

The invention relates to a method for preparing co-processed excipient granules using a co-rotating twin-screw extruder, wherein at least one binder and at least one superdisintegrant are granulated together, and wherein the binder and the superdisintegrant are introduced into the extruder in differ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	JASPERS, Maarten, HEBBINK, Gerrit Albert, VAN HAANDEL, Mara Maria Wilhelmina, VAN LAARHOVEN, Bas, KULKARNI, Sri Sharath
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The invention relates to a method for preparing co-processed excipient granules using a co-rotating twin-screw extruder, wherein at least one binder and at least one superdisintegrant are granulated together, and wherein the binder and the superdisintegrant are introduced into the extruder in different points. The invention also relates to co-processed excipient granules obtained or obtainable by the method. The invention further relates to the use of the co-processed excipient granules in a tableting process.