METHOD OF PIERCING SEAL FOR SAMPLE TESTING

Disclosed herein include methods, compositions, and kits suitable for use in sample testing. The sample testing systems can comprise a cartridge body to receive a sample, at least one reaction chamber coupled to the cartridge body, and at least one seal between the cartridge body and the at least on...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Truitt, Patrick Walter, Shedlosky, Alyssa Nicolaisen, Downie, Patrick, Lentz, Ammon D
Format: Patent
Sprache:eng
Schlagworte:
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Beschreibung
Zusammenfassung:Disclosed herein include methods, compositions, and kits suitable for use in sample testing. The sample testing systems can comprise a cartridge body to receive a sample, at least one reaction chamber coupled to the cartridge body, and at least one seal between the cartridge body and the at least one reaction chamber. The sample testing system can comprise a sample dispensing mechanism operable to disrupt the at least one seal to dispense a predetermined sub-volume of sample fluid from the cartridge body into the at least one reaction chamber. The sample dispensing mechanism can comprise a dispense rod comprising at least one piercing tip that disrupts the at least one seal by forming at least one opening therein. The piercing tips can comprise a geometry configured to generate a large opening in the at least one seal.