ENGINEERED 3-O-KINASE VARIANTS AND METHODS OF USE

The present invention provides engineered 3′O-kinase polypeptides useful for construction of materials used in template-independent polynucleotide synthesis, as well as compositions and methods of utilizing these engineered polypeptides. The present disclosure also describes one-pot methods for conv...

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Hauptverfasser: Forgel, Stephanie Marie, Watts, David, Krawczyk, Mikayla, Shoubber, Amani, Provencher, Philip, Vroom, Jonathan, Knight, Anders Matthew, Entwistle, David, Wong, Leland
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creator Forgel, Stephanie Marie
Watts, David
Krawczyk, Mikayla
Shoubber, Amani
Provencher, Philip
Vroom, Jonathan
Knight, Anders Matthew
Entwistle, David
Wong, Leland
description The present invention provides engineered 3′O-kinase polypeptides useful for construction of materials used in template-independent polynucleotide synthesis, as well as compositions and methods of utilizing these engineered polypeptides. The present disclosure also describes one-pot methods for conversion of a natural or modified nucleoside to a nucleoside tetraphosphate or NQP.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title ENGINEERED 3-O-KINASE VARIANTS AND METHODS OF USE
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