MACROCYCLES AS CFTR MODULATORS
The present invention relates to macrocyclic compounds of Formula (I)wherein Ar1, Ar2, R1, R2, R3, R4, and X are as described in the description, their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or mor...
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| creator | WAGNER, Clemens BOLLI, Martin KIMMERLIN, Thierry SIENDT, Hervé BROTSCHI, Christine COMMANDEUR, Malgorzata WILLIAMS, Jodi T SPRINGER, Jasper GATFIELD, John WEGERT, Anita |
| description | The present invention relates to macrocyclic compounds of Formula (I)wherein Ar1, Ar2, R1, R2, R3, R4, and X are as described in the description, their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of Formula (I), and especially to their use as modulators of CFTR. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | MACROCYCLES AS CFTR MODULATORS |
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