HETEROTANDEM BICYCLIC PEPTIDE COMPLEXES

The present invention relates to heterotandem bicyclic peptide complexes which comprise a first peptide ligand, which binds to a component present on a cancer cell, conjugated via a linker to one or more second peptide ligands, which bind to one or more components present on a natural killer (NK) ce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	BRANDISH, Phil, DUFORT, Fay, UHLENBROICH, Sandra, MCDONNELL, Kevin, REPASH, Liz, KEEN, Nicholas, GAYNOR, Katie, CHEN, Liuhong, MUDD, Gemma, LEITHEISER, Chris
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to heterotandem bicyclic peptide complexes which comprise a first peptide ligand, which binds to a component present on a cancer cell, conjugated via a linker to one or more second peptide ligands, which bind to one or more components present on a natural killer (NK) cell. The invention also relates to the use of said heterotandem bicyclic peptide complexes in preventing, suppressing or treating cancer.