CDK INHIBITORS AND METHODS OF USE THEREOF

The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of CDK enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders as...

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Hauptverfasser: Taylor, Alexander M, He, Jing, Briggs, Timothy F, Kelley, Brian P, Pabon, Nicolas A, McLean, Thomas H, Boezio, Alessandro, Evans, Catherine A, Fridrich, Cary Griffin, Kurukulasuriya, Ravi, Lescarbeau, Andre, Krueger, Elaine B
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creator Taylor, Alexander M
He, Jing
Briggs, Timothy F
Kelley, Brian P
Pabon, Nicolas A
McLean, Thomas H
Boezio, Alessandro
Evans, Catherine A
Fridrich, Cary Griffin
Kurukulasuriya, Ravi
Lescarbeau, Andre
Krueger, Elaine B
description The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of CDK enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with CDK signaling with the compounds and compositions of the disclosure.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title CDK INHIBITORS AND METHODS OF USE THEREOF
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