CDK INHIBITORS AND METHODS OF USE THEREOF

CDK INHIBITORS AND METHODS OF USE THEREOF

The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of CDK enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders as...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Taylor, Alexander M, He, Jing, Briggs, Timothy F, Kelley, Brian P, Pabon, Nicolas A, McLean, Thomas H, Boezio, Alessandro, Evans, Catherine A, Fridrich, Cary Griffin, Kurukulasuriya, Ravi, Lescarbeau, Andre, Krueger, Elaine B
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of CDK enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with CDK signaling with the compounds and compositions of the disclosure.