PROCESS FOR PREPARATION OF CABOZANTINIB

The present invention provides for novel amorphous solid dispersions of form of cabozantinib malate, and a pharmaceutically acceptable excipient and process for the preparation of cabozantinib malate. The invention also provides a novel crystalline polymorph of cabozantinib.

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Bibliographische Detailangaben
Hauptverfasser:	MATTI, Lankeswararao, NAIR, Ranjeet, BHAT, Ramakrishna Parameshwar, CHETTY, Jithendrababu Raghunadha, KUMAR, Narasimman, PATEL, Pratik Rameshchandra, DEVAIAH, Venu Thirunelimada
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention provides for novel amorphous solid dispersions of form of cabozantinib malate, and a pharmaceutically acceptable excipient and process for the preparation of cabozantinib malate. The invention also provides a novel crystalline polymorph of cabozantinib.