TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES

Disclosed herein are compounds of the Formula (I) or (II) or (III):Also disclosed are methods for stimulating an immune response, inducing an anti-tumor immune response, and treating an infectious disease in a subject by administering a therapeutically effective amount of a compound disclosed herein...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: OLAWODE, Emmanuel, TUMEY, Lawrence Nathan
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed herein are compounds of the Formula (I) or (II) or (III):Also disclosed are methods for stimulating an immune response, inducing an anti-tumor immune response, and treating an infectious disease in a subject by administering a therapeutically effective amount of a compound disclosed herein. Also disclosed are methods of treating a tumor or abnormal cell proliferation by administering a therapeutically effective amount of a compound disclosed herein under conditions effective to treat a tumor or abnormal cell proliferation.