MODIFIED-RELEASE SILODOSIN COMPOSITIONS AND USE THEREOF IN METHODS FOR MALE CONTRACEPTION

The present disclosure relates to modified-release silodosin compositions including at least one pellet that comprises a silodosin drug layer and an extended-release coating.The drug layer can comprise silodosin and a binder. The pellet can further comprise a sealing coating. The pellet can further...

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Bibliographische Detailangaben
Hauptverfasser:	TULLI-CORTES, Marguerite, EL GLAOUI, Mehdi, REVEL, Jérôme, ANGOT, Stéphanie, AGATHON-MERIAU, Véronique, EL GLAOUI, Guillaume
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present disclosure relates to modified-release silodosin compositions including at least one pellet that comprises a silodosin drug layer and an extended-release coating.The drug layer can comprise silodosin and a binder. The pellet can further comprise a sealing coating. The pellet can further comprise an enteric coating.The present disclosure further relates to the use of the compositions described in methods for male contraception.The present disclosure further relates to processes for manufacturing a pellet or dosage form as described herein.