METHODS OF TREATING CANCER WITH ANTIBODIES AGAINST TIM3

This disclosure provides a method for treating a subject afflicted with a tumor or a cancer, wherein the method comprises administering to the subject therapeutically effective amounts of an anti-TIM3 antibody, alone or in combination with an inhibitor of the PD-1 signaling pathway (e.g., anti-PD-1...

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Hauptverfasser:	KUHNE, Michelle Renne, HAN, Michelle Minhua, DEVAUX, Brigitte, KORMAN, Alan J, DEYANOVA, Ekaterina, DENG, Andy X, SHEPPARD, Paul O, SELBY, Mark J, CHUNTHARAPAI, Anan, LI, Huiming, JACKSON, Jeffrey R, SCHEBYE, Xiao Min, ARDOUREL, Daniel F, FLEMING, Ronald A, PATAH, Poliana, CHEN, Guodong, BEE, Christine, HUANG, Richard Yu-Cheng, TRUONG, Hong-An
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This disclosure provides a method for treating a subject afflicted with a tumor or a cancer, wherein the method comprises administering to the subject therapeutically effective amounts of an anti-TIM3 antibody, alone or in combination with an inhibitor of the PD-1 signaling pathway (e.g., anti-PD-1 antibody). In some embodiments, the antibody is administered as a flat dose or a weight-based dose.