DISPOSABLE CARTRIDGE FOR PERFORMING AN AUTOMATIC SAMPLE PREPARATION

A disposable cartridge for performing an automatic sample preparation, said cartridge comprising: a barrel housing layer (L2) to host extruded barrels for housing liquids (reagents), each barrel being a piston actuated barrel sealed with a frangible seal, said barrel housing layer receiving and stor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jain, Prakhar, Kumaran, Vishwanth, Paul, Saikat, Abbasi, Usama Ahmed
Format: Patent
Sprache:eng
Schlagworte:
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Beschreibung
Zusammenfassung:A disposable cartridge for performing an automatic sample preparation, said cartridge comprising: a barrel housing layer (L2) to host extruded barrels for housing liquids (reagents), each barrel being a piston actuated barrel sealed with a frangible seal, said barrel housing layer receiving and storing a blood sample to be tested; a puncturing layer (L4) to host needles in order to puncture said frangible seal upon receiving a force from its operative bottom side; a liquid flow channel layer (L5) with liquid flow channels and valves, for providing micro-channels for splitting, routing, and metering of said samples with reagents; a soft membrane (L6) to work as an interface for mixing liquids and for blocking fluidic channels to prevent flow of fluids in channels of choice; and an actuation layer (L8) to provide actuation force for closing or opening of said valves.