METHOD AND SYSTEM FOR CROSS-REFERENCING OF TWO-DIMENSIONAL (2D) ULTRASOUND SCANS OF A TISSUE VOLUME

A method for cross-referencing of 2D ultrasound scans of a tissue volume comprises generating first and second 2D representations of a target anatomy, respectively, from first and second series of 2D ultrasound images of the tissue volume generated. The method includes generating first and second simulated 2D representations of the target anatomy, respectively, from the second and first series of 2D ultrasound images. The 2D and simulated 2D representations are processed to at least substantially match pixel positions in the 2D and simulated 2D representations associated with the target anatomy. The method includes determining first and second correspondence transformation matrices from the processed 2D and simulated 2D representations, and using the first and second correspondence transformation matrices to determine, for a location in the second series of 2D ultrasound images associated with the target anatomy, a corresponding location in the first series of 2D ultrasound images.