INHIBITORS OF ANTIGEN PRESENTATION BY MHC CLASS II HLA-DRB115:01 MOLECULES WITH ENHANCED METABOLIC STABILITY

INHIBITORS OF ANTIGEN PRESENTATION BY MHC CLASS II HLA-DRB115:01 MOLECULES WITH ENHANCED METABOLIC STABILITY

Provided are compounds, pharmaceutical compositions containing such compounds and methods for using the compounds the treatment or prevention of autoimmune diseases and disorders associated with antigen presentation by MHC Class II HLA-DRB1*15:O1 and furthermore, have improved metabolic stability co...

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Hauptverfasser: SELF, Christopher R, SUN, Yanjun, OLSON, Gary L
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Zusammenfassung:Provided are compounds, pharmaceutical compositions containing such compounds and methods for using the compounds the treatment or prevention of autoimmune diseases and disorders associated with antigen presentation by MHC Class II HLA-DRB1*15:O1 and furthermore, have improved metabolic stability compared to previous inhibitors.