BINDING MOLECULES FOR THE TREATMENT OF CANCER

This invention relates to binding molecules that bind specifically to TNF-related apoptosis-inducing ligand receptor 2 (TRAILR2) and cadherin-17 (CDH17) and their use in medicine, pharmaceutical compositions comprising the same, and methods of using the same as agents for treatment and/or prevention...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	SHAABAN, Abdulsalam, ERYILMAZ, Ertan, GARCIA-MARTINEZ, Juan Manuel, HO, Jason, VOYNOV, Vladimir, FENN, Timothy, KUENKELE, Klaus-Peter, WERNITZNIG, Andreas, GANESAN, Rajkumar, KOESSL, Christian, SEN, Saurabh
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates to binding molecules that bind specifically to TNF-related apoptosis-inducing ligand receptor 2 (TRAILR2) and cadherin-17 (CDH17) and their use in medicine, pharmaceutical compositions comprising the same, and methods of using the same as agents for treatment and/or prevention of cancer.