A METHOD AND SYSTEM FOR INTEGRATED AND CONTINUOUS VIRAL FILTRATION, CONCENTRATION AND BUFFER EXCHANGE

A METHOD AND SYSTEM FOR INTEGRATED AND CONTINUOUS VIRAL FILTRATION, CONCENTRATION AND BUFFER EXCHANGE

A method and system for integrated and continuous viral filtration and biological product concentration, including an initial purification system coupled to a final purification system. The initial purification system includes a viral reduction filtration (VRF) skid, while the final purification sys...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GODFREY, Scott, KHOURI, Joelle, ZHU, Min, IKON, Nikita, OROZCO, Raquel, CAPRON, Charles
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:A method and system for integrated and continuous viral filtration and biological product concentration, including an initial purification system coupled to a final purification system. The initial purification system includes a viral reduction filtration (VRF) skid, while the final purification system includes a single-pass tangential filtration-diafiltration (SPTFF-DF) skid.