LIVER SPECIFIC DELIVERY OF MESSENGER RNA

Disclosed herein are compositions and methods of modulating the expression of gene or the production of a protein by transfecting target cells with nucleic acids. The compositions disclosed herein demonstrate a high transfection efficacy and are capable of ameliorating diseases associated with prote...

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Bibliographische Detailangaben
Hauptverfasser: Guild, Braydon Charles, Heartlein, Michael, DeRosa, Frank
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed herein are compositions and methods of modulating the expression of gene or the production of a protein by transfecting target cells with nucleic acids. The compositions disclosed herein demonstrate a high transfection efficacy and are capable of ameliorating diseases associated with protein or enzyme deficiencies.