ARTIFICIAL EXPRESSION CONSTRUCTS FOR MODULATING GENE EXPRESSION IN GABAERGIC NEURONS AND ASTROCYTES

Artificial expression constructs for modulating gene expression in GABAergic neurons and astrocytes are described. The artificial expression constructs can be used to express SLC6A1 for the treatment of SLC6A1-associated disorders, among other uses.

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Hauptverfasser: Gore, Bryan, Levi, Boaz P, Martinez, Refugio, Machen, Deja, Mich, John K, Ting, Jonathan, Lein, Edward Sebastian
Format: Patent
Sprache:eng
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Zusammenfassung:Artificial expression constructs for modulating gene expression in GABAergic neurons and astrocytes are described. The artificial expression constructs can be used to express SLC6A1 for the treatment of SLC6A1-associated disorders, among other uses.