STAPLED PEPTIDES AND METHODS THEREOF

Among other things, the present disclosure provides various agents. In some embodiments, provided agents can bind to beta-catenin. In some embodiments, the present disclosure provides technologies for modulating beta-catenin functions. In some embodiments, the present disclosure provides technologie...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McGee, John Hanney, Li, Zhi, Jewett, Ivan Tucker, Zhang, Yue-Mei, White, Brian Halbert, Conrady, Deborah Gail, Alfaro-Lopez, Lorenzo Josue, Si, Yaguang, Tremblay, Martin Robert, Cappucci, Sarah Isabelle
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Among other things, the present disclosure provides various agents. In some embodiments, provided agents can bind to beta-catenin. In some embodiments, the present disclosure provides technologies for modulating beta-catenin functions. In some embodiments, the present disclosure provides technologies for preventing and/or treating conditions, disorders or diseases associated with beta-catenin. In some embodiments, the present disclosure provides designed amino acids which can provide improved properties and/or activities. In some embodiments, the present disclosure provides agents comprising such amino acids.