ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF

ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF

The present disclosure relates to isoxazolidines and their use as receptor-interacting protein kinase 1 inhibitors, for example in the treatment of diseases and disorders mediated by RIP kinase 1.

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Bibliographische Detailangaben
Hauptverfasser: SZILLAT, Hauke, HEINELT, Uwe, RACKELMANN, Nils, MENDEZ-PEREZ, Maria, RITTER, Kurt, DEFOSSA, Elisabeth, ZECH, Gernot, MATTER, Hans
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present disclosure relates to isoxazolidines and their use as receptor-interacting protein kinase 1 inhibitors, for example in the treatment of diseases and disorders mediated by RIP kinase 1.