Heteroaryl Compounds as Ligand Directed Degraders of IRAK4

Provided herein are compounds and compositions thereof for modulating IRAK4. In some embodiments, the compounds and compositions are provided for treatment of inflammatory or autoimmune diseases.

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Bibliographische Detailangaben
Hauptverfasser:	Meng, Yilin, Ellis, Michael, Gormisky, Paul, Siu, Tony, Hager, Harry, Hu, Lingbowei, Davies, Geraint, Rasmusson, Timothy, van der Mei, Farid, Ma, Rulin
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	Provided herein are compounds and compositions thereof for modulating IRAK4. In some embodiments, the compounds and compositions are provided for treatment of inflammatory or autoimmune diseases.