SELF-LIMITING, SEX-SPECIFIC GENE AND METHODS OF USING

The invention provides a splice control module for sex-specific splicing and expression of a gene of interest. In certain embodiments, a dsx-based splice control module is used to express a lethal gene in an insect that is spliced in a sex-specific manner to impart lethality to female insects but no...

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Hauptverfasser: WARNER, Simon, ALPHEY, Luke, COLLADO, Amandine, MATZEN, Kelly, DAFA'ALLA, Tarig, SPINNER, Sian
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides a splice control module for sex-specific splicing and expression of a gene of interest. In certain embodiments, a dsx-based splice control module is used to express a lethal gene in an insect that is spliced in a sex-specific manner to impart lethality to female insects but not male insects.