COMBINATION THERAPIES FOR TREATING CANCER

Provided are methods of treating cancer that comprise administering a polypeptide (e.g. a fusion polypeptide) that comprises a SIRPα D1 domain variant and an Fc domain variant in combination with at least one chemotherapy agent and/or at least one therapeutic antibody. Also provided are related kits...

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Bibliographische Detailangaben
Hauptverfasser: RANDOLPH, Sophia, PONS, Jaume, KUO, Tracy Chia-Chien, WAN, Hong, SIM, Bang Janet
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Provided are methods of treating cancer that comprise administering a polypeptide (e.g. a fusion polypeptide) that comprises a SIRPα D1 domain variant and an Fc domain variant in combination with at least one chemotherapy agent and/or at least one therapeutic antibody. Also provided are related kits.