PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS

Disclosed are compounds of Formula (I):or pharmaceutically acceptable salts or solvates thereof, wherein R1, R3, X, Y, Z, and W are as defined herein. The compounds are, for example, inhibitors of WRN helicase and useful in treating a proliferative disease, such as cancer.

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	Malmstrom, Robert, Owyang, Zach, Kikuchi, Shota, Rogness, Don, Burgess, Larry, Lamb, Kelsey, Green, Jason, Horning, Benjamin, Lam, Betty, Weinstein, David
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Disclosed are compounds of Formula (I):or pharmaceutically acceptable salts or solvates thereof, wherein R1, R3, X, Y, Z, and W are as defined herein. The compounds are, for example, inhibitors of WRN helicase and useful in treating a proliferative disease, such as cancer.