ANTI-HUMAN B CELL MATURATION ANTIGEN (BCMA) ANTIBODIES AND THEIR USE IN IMMUNOHISTOCHEMISTRY (IHC)

ANTI-HUMAN B CELL MATURATION ANTIGEN (BCMA) ANTIBODIES AND THEIR USE IN IMMUNOHISTOCHEMISTRY (IHC)

In alternative embodiments, provided are chimeric or recombinant anti-human B-cell maturation antigen (BCMA, or BCM) polypeptide (also called tumor necrosis factor receptor superfamily member 17 (TNERSF17)) antibodies, including products of manufacture and kits comprising them, and methods for makin...

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Bibliographische Detailangaben
Hauptverfasser: HAGEDORN-OLSEN, Tine, SORENSEN, Morten Draeby, HOFF, Kirsten
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Beschreibung
Zusammenfassung:In alternative embodiments, provided are chimeric or recombinant anti-human B-cell maturation antigen (BCMA, or BCM) polypeptide (also called tumor necrosis factor receptor superfamily member 17 (TNERSF17)) antibodies, including products of manufacture and kits comprising them, and methods for making and using them, including for example their use in the detection or diagnosis of a cancer or other conditions. In alternative embodiments, anti-BCMA antibodies as provided herein are used together with an agent for determining whether BCMA expression or activity is reduced or absent.