ENZYME INHIBITORS

The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in medicine; and methods of treating patients with such compounds; wherein A, W, R5, n, Z, X, Y and B are as defined herein. The present invention also relates to compounds usef...

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Hauptverfasser: NORTH, Carl Leslie, HODGSON, Simon Teanby, ROOKER, David Philip, BIRCH, Louise Michelle, PITTAWAY, Rachael, OBARA, Alicja Stela, ROE, Michael Bryan, EDWARDS, Hannah Joy, YANG, Xuezheng, PICHOWICZ, Mark, SMITH, Alun John, CHILDS, Mitchell Lewis, GREVES, William Jack, CLARK, David Edward, WRIGGLESWORTH, Joseph William, STOCKS, Michael John, THROUP, Adam Eric, EVANS, David Michael, MAZZACANI, Alessandro, DAVIE, Rebecca Louise
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in medicine; and methods of treating patients with such compounds; wherein A, W, R5, n, Z, X, Y and B are as defined herein. The present invention also relates to compounds useful as synthetic intermediates of compounds of formula (I).