COMPOSITION FOR PREVENTION AND TREATING DEMENTIA THROUGH THE COMBINATION OF PDE5 INHIBITORS AND GLUCOCORTICOID RECEPTOR ANTAGONISTS

The present invention relates to the removal of amyloid-beta by the combination of mirodenafil, a phosphodiesterase 5 inhibitors (PDE5 inhibitors), and CORT-108297, a Glucocorticoid Receptor (GR) Antagonists for treatment of Alzheimer's disease or dementia.

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Bibliographische Detailangaben
Hauptverfasser: Kang, Byungwoo, CHOUNG, Jaijun
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to the removal of amyloid-beta by the combination of mirodenafil, a phosphodiesterase 5 inhibitors (PDE5 inhibitors), and CORT-108297, a Glucocorticoid Receptor (GR) Antagonists for treatment of Alzheimer's disease or dementia.