KRAS G12C INHIBITORS AND METHODS OF USING THE SAME

Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

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Bibliographische Detailangaben
Hauptverfasser:	SIEGMUND, Aaron C, SHIN, Youngsook, ALLEN, Jennifer Rebecca, AMEGADZIE, Albert, WANG, Hui-Ling, NGUYEN, Thomas T, LANMAN, Brian Alan, CHEN, Jian Jeffrey, MINATTI, Ana Elena, BOOKER, Shon, PICKRELL, Alexander J, WURZ, Ryan Paul, WALTON, Mary, REED, Anthony B, TAMAYO, Nuria A, LOW, Jonathan D, FROHN, Michael J, CEE, Victor J, LOPEZ, Patricia, ALLEN, John Gordon, XUE, Qiufen, MA, Vu Van, KOPECKY, David John, TEGLEY, Christopher M, LIU, Longbin, GOODMAN, Clifford, CHEN, Ning, NISHIMURA, Nobuko
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.